A 21-year-old woman is evaluated in the emergency room after reporting she was sexually assaulted by a single male assailant. The male assailant is arrested and agrees to laboratory testing. The woman who suffered the sexual assault has never received the hepatitis B vaccine. Empiric treatment for sexually transmitted infections is given, laboratory tests are ordered, and HIV postexposure prophylaxis is started. After 24 hours, the laboratory test results for the survivor and assailant become available; based on these results, the HIV postexposure prophylaxis (PEP) is discontinued. The results are shown below
Laboratory Test | Sexual Assault Survivor | Alleged Assailant |
---|---|---|
Hepatitis B surface antibody (anti-HBs) | Negative | Negative |
Hepatitis B surface antigen (HBsAg) | Negative | Positive |
Hepatitis B core antibody (anti-HBc) | Negative | Positive |
Hepatitis C antibody | Negative | Negative |
HIV-1/2 antigen-antibody | Negative | Negative |
Which one of the following would be the recommended approach to prevent hepatitis B virus (HBV) infection for this woman?
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June 23rd, 2025