A 23-year-old man who had sex with a woman 1 week prior is evaluated in a clinic for symptoms of urethral discharge. Physical examination shows evidence of a mucopurulent discharge (Figure 1). A first-void urine leukocyte esterase test is positive, but the clinic does not have the capacity for point-of-care staining of urethral secretions. A nucleic acid amplification test (NAAT) is sent for Neisseria gonorrhoeae and Chlamydia trachomatis, and the result is pending. He weighs 86 kg.