National STD CurriculumLogo

Lesson 22. Penicillin Allergy

  PDF Share

References

  • Gonzalez-Estrada A, Radojicic C. Penicillin allergy: A practical guide for clinicians. Cleve Clin J Med. 2015;82:295-300.

Tables

Table 1.

Gell and Coombs Classification of Hypersensitivity Reactions
Type of Reactions Hypersensitivity Mediated by Time of Onset Examples
IgE-mediated Type I IgE antibodies Within 1 hour Anaphylaxis
Non-IgE-mediated Type II Cytotoxic Hours to days Hemolytic anemia
Non-IgE-mediated Type III Immune complex 7-21 days Serum sickness
Non-IgE-mediated Type IV Cell-mediated Days to weeks Maculopapular rash
Stevens-Johnson syndrome
Toxic epidermal necrolysis

IgE = immunoglobulin E
Source:
  • Gonzalez-Estrada A, Radojicic C. Penicillin allergy: A practical guide for clinicians. Cleve Clin J Med. 2015;82:295-300. [PubMed Abstract]

Share by e-mail

Check
-On-
Learning
Questions
The Check-on-Learning Questions are short and topic related. They are meant to help you stay on track throughout each lesson and check your understanding of key concepts.

You must be signed in to customize your interaction with these questions.

Since you've received 80% or better on this quiz, you may claim continuing education credit.

You seem to have a popup blocker enabled. If you want to skip this dialog please Always allow popup windows for the online course.